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2015 Research Publications

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  1. Zhang, Y., Zhang, J., Yang, J., Wang, Y., Zhang, L., ....., Chung, B. H., ....., Ng, I. O., Garcia-Barcelo, M. M., Cherny, S. S., Tam, P. K., Sham, P. C., Yang, S., Ye, D. Q., Cui, Y., Zhang, X. J., Lau, Y. L., and Yang, W. (2015) Meta-analysis of GWAS on two Chinese populations followed by replication identifies novel genetic variants on the X chromosome associated with systemic lupus erythematosus, Human molecular genetics 24, 274-284.


  2. Zhang, Y., Yang, J., Zhang, J., Sun, L., Hirankarn, N., ….., Chung, B. H., ….., Ng, I. O., Garcia-Barcelo, M. M., Cherny, S. S., Cui, Y., Sham, P. C., Yang, S., Ye, D. Q., Zhang, X. J., Lau, Y. L., and Yang, W. (2015) Genome-wide search followed by replication reveals genetic interaction of CD80 and ALOX5AP associated with systemic lupus erythematosus in Asian populations, Annals of the rheumatic diseases.


  3. Zhang, Y., Wang, Y. F., Yang, J., Zhang, J., Sun, L., Hirankarn, N., ….., Chung, B. H., ….., Ng, I. O., Garcia-Barcelo, M. M., Cherny, S. S., Tam, P. K., Sham, P. C., Yang, S., Ye, D. Q., Cui, Y., Zhang, X. J., Yang, W., and Lau, Y. L. (2015) Meta-analysis of two Chinese populations identifies an autoimmune disease risk allele in 22q11.21 as associated with systemic lupus erythematosus, Arthritis research & therapy 17, 67.


  4. Zhang, Y., Liang, X., Liao, S., Wang, W., Wang, J., Li, X., Ding, Y., Liang, Y., Gao, F., Yang, M., Fu, Q., Xu, A., Chai, Y. H., He, J., Tse, H. F., and Lian, Q. (2015) Potent Paracrine Effects of human induced Pluripotent Stem Cell-derived Mesenchymal Stem Cells Attenuate Doxorubicin-induced Cardiomyopathy, Scientific reports 5, 11235.


  5. Zhang, J., Zhang, L., Zhang, Y., Yang, J., Guo, M., Sun, L., Pan, H. F., Hirankarn, N., Ying, D., Zeng, S., Lee, T. L., Lau, C. S., Chan, T. M., Leung, A. M., Mok, C. C., Wong, S. N., Lee, K. W., Ho, M. H., Lee, P. P., Chung, B. H., Chong, C. Y., Wong, R. W., Mok, M. Y., Wong, W. H., Tong, K. L., Tse, N. K., Li, X. P., Avihingsanon, Y., Rianthavorn, P., Deekajorndej, T., Suphapeetiporn, K., Shotelersuk, V., Ying, S. K., Fung, S. K., Lai, W. M., Garcia-Barcelo, M. M., Cherny, S. S., Sham, P. C., Cui, Y., Yang, S., Ye, D. Q., Zhang, X. J., Lau, Y. L., and Yang, W. (2015) Gene-Based Meta-Analysis of Genome-Wide Association Study Data Identifies Independent Single-Nucleotide Polymorphisms in ANXA6 as Being Associated With Systemic Lupus Erythematosus in Asian Populations, Arthritis & rheumatology 67, 2966-2977.


  6. Yu, Y., Qin, J., Chen, D., Wang, H., Wang, J., and Yu, Y. (2015) Chronic cardiovascular disease-associated gene network analysis in human umbilical vein endothelial cells exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin, Cardiovascular toxicology 15, 157-171.


  7. Xiao, B., Gu, S. M., Li, M. J., Li, J., Tao, B., Wang, Y., Wang, Y., Zuo, S., Shen, Y., Yu, Y., Chen, D., Chen, G., Kong, D., Tang, J., Liu, Q., Chen, D. R., Liu, Y., Alberti, S., Dovizio, M., Landolfi, R., Mucci, L., Miao, P. Z., Gao, P., Zhu, D. L., Wang, J., Li, B., Patrignani, P., and Yu, Y. (2015) Rare SNP rs12731181 in the miR-590-3p Target Site of the Prostaglandin F2alpha Receptor Gene Confers Risk for Essential Hypertension in the Han Chinese Population, Arteriosclerosis, thrombosis, and vascular biology 35, 1687-1695.


  8. Wei, Z., Chang, X., and Wang, J. (2015) Advanced Computational Approaches for Medical Genetics and Genomics, BioMed research international 2015, 705469.


  9. Wang, Y., Tsang, C. N., Xu, F., Kong, P. W., Hu, L., Wang, J., Chu, I. K., Li, H., and Sun, H. (2015) Bio-coordination of bismuth in Helicobacter pylori revealed by immobilized metal affinity chromatography, Chemical communications 51, 16479-16482.


  10. Wang, P., Qin, J., Qin, Y., Zhu, Y., Wang, L. Y., Li, M. J., Zhang, M. Q., and Wang, J. (2015) ChIP-Array 2: integrating multiple omics data to construct gene regulatory networks, Nucleic acids research 43, W264-269.


  11. Van der Sluis, S., Dolan, C. V., Li, J., Song, Y., Sham, P., Posthuma, D., and Li, M. X. (2015) MGAS: a powerful tool for multivariate gene-based genome-wide association analysis, Bioinformatics 31, 1007-1015.


  12. Toulopoulou, T., van Haren, N., Zhang, X., Sham, P. C., Cherny, S. S., Campbell, D. D., Picchioni, M., Murray, R., Boomsma, D. I., Pol, H. H., Brouwer, R., Schnack, H., Fananas, L., Sauer, H., Nenadic, I., Weisbrod, M., Cannon, T. D., and Kahn, R. S. (2015) Reciprocal causation models of cognitive vs volumetric cerebral intermediate phenotypes for schizophrenia in a pan-European twin cohort, Molecular psychiatry 20, 1386-1396.


  13. Sha'ari, H. M., Haerian, B. S., Baum, L., Tan, H. J., Rafia, M. H., Kwan, P., Cherny, S. S., Sham, P. C., Gui, H., Raymond, A. A., Lim, K. S., and Mohamed, Z. (2015) Association of BDNF Polymorphisms with the Risk of Epilepsy: a Multicenter Study, Molecular neurobiology.


  14. Sampson, J. N., Wheeler, W. A., Yeager, M., Panagiotou, O., Wang, Z., ….., Wang, J., ….., Zhang, Y., ….., D. T., Slager, S. L., Chanock, S. J., and Chatterjee, N. (2015) Analysis of Heritability and Shared Heritability Based on Genome-Wide Association Studies for Thirteen Cancer Types, Journal of the National Cancer Institute 107.


  15. Poon, M. W., He, J., Fang, X., Zhang, Z., Wang, W., Wang, J., Qiu, F., Tse, H. F., Li, W., Liu, Z., and Lian, Q. (2015) Human Ocular Epithelial Cells Endogenously Expressing SOX2 and OCT4 Yield High Efficiency of Pluripotency Reprogramming, PloS one 10, e0131288.


  16. Peng, L., Zhao, Q., Li, Q. B., Li, M. X., Li, C. X., Xu, T. T., Jing, X. Y., Zhu, X., Wang, Y., Li, F. C., Liu, R. H., Zhong, C., Pan, Q. H., Zeng, B. H., Liao, Q. J., Hu, B., Hu, Z. X., Huang, Y. S., Sham, P., Liu, J. S., Xu, S. H., Wang, J., Gao, Z. L., and Wang, Y. M. (2015) The p.Ser267Phe Variant in SLC10A1 Is Associated With Resistance to Chronic Hepatitis B, Hepatology 61, 1251-1260.


  17. Nelson, M. R., Tipney, H., Painter, J. L., Shen, J., Nicoletti, P., Shen, Y., Floratos, A., Sham, P. C., Li, M. J., Wang, J., Cardon, L. R., Whittaker, J. C., and Sanseau, P. (2015) The support of human genetic evidence for approved drug indications, Nature genetics 47, 856-860.


  18. Machiela, M. J., Hsiung, C. A., Shu, X. O., Seow, W. J., Wang, Z., ….., Wang, J., ….., Fraumeni, J. F., Jr., Zheng, W., Lin, D., Chanock, S. J., Rothman, N., and Lan, Q. (2015) Genetic variants associated with longer telomere length are associated with increased lung cancer risk among never-smoking women in Asia: a report from the female lung cancer consortium in Asia, International journal of cancer. Journal international du cancer 137, 311-319.


  19. Liu, W., Wong, J. K., He, Q., Wong, E. H., Tang, C. S., Zhang, R., So, M. T., Wong, K. K., Nicholls, J., Cherny, S. S., Sham, P. C., Tam, P. K., Garcia-Barcelo, M. M., and Xia, H. (2015) Chinese family with diffuse oesophageal leiomyomatosis: a new COL4A5/COL4A6 deletion and a case of gonosomal mosaicism, BMC medical genetics 16, 49.


  20. Li, M. J., and Wang, J. (2015) Current trend of annotating single nucleotide variation in humans--A case study on SNVrap, Methods 79-80, 32-40.


  21. Li, M. J., Deng, J., Wang, P., Yang, W., Ho, S. L., Sham, P. C., Wang, J., and Li, M. (2015) wKGGSeq: A Comprehensive Strategy-Based and Disease-Targeted Online Framework to Facilitate Exome Sequencing Studies of Inherited Disorders, Human mutation 36, 496-503.


  22. Li, J., Sham, P. C., Song, Y., and Li, M. (2015) SPS: A Simulation Tool for Calculating Power of Set-Based Genetic Association Tests, Genetic epidemiology 39, 395-397.


  23. Kwan, J. S., Li, M. X., Deng, J. E., and Sham, P. C. (2015) FAPI: Fast and Accurate P-value Imputation for genome-wide association study, European journal of human genetics : EJHG.


  24. Hu, J., Zhao, Z. Y., Yalamanchili, H. K., Wang, J. W., Ye, K., and Fan, X. D. (2015) Bayesian Detection of Embryonic Gene Expression Onset in C. Elegans, Ann Appl Stat 9, 950-968.


  25. Ho, P. W., Pang, S. Y., Li, M., Tse, Z. H., Kung, M. H., Sham, P. C., and Ho, S. L. (2015) PMCA4 (ATP2B4) mutation in familial spastic paraplegia causes delay in intracellular calcium extrusion, Brain and behavior 5, e00321.


  26. Haerian, B. S., Baum, L., Kwan, P., Cherny, S. S., Shin, J. G., Kim, S. E., Han, B. G., Tan, H. J., Raymond, A. A., Tan, C. T., and Mohamed, Z. (2015) Contribution of GABRG2 Polymorphisms to Risk of Epilepsy and Febrile Seizure: a Multicenter Cohort Study and Meta-analysis, Molecular neurobiology.


  27. Gan, J., Wang, C., Jin, Y., Guo, Y., Xu, F., Zhu, Q., Ding, L., Shang, H., Wang, J., Wei, F., Cai, Q., and Robertson, E. S. (2015) Proteomic profiling identifies the SIM-associated complex of KSHV-encoded LANA, Proteomics 15, 2023-2037.


  28. Cheung, C. L., Sahni, S., Cheung, B. M., Sing, C. W., and Wong, I. C. (2015) Vitamin K intake and mortality in people with chronic kidney disease from NHANES III, Clinical nutrition 34, 235-240.


  29. Cheung, C. L., Lam, K. S., and Cheung, B. M. (2015) Evaluation of Cutpoints for Low Lean Mass and Slow Gait Speed in Predicting Death in the National Health and Nutrition Examination Survey 1999-2004, The journals of gerontology. Series A, Biological sciences and medical sciences.


  30. Campbell, D. D., Porsch, R. M., Cherny, S. S., Capra, V., Merello, E., De Marco, P., Sham, P. C., and Garcia-Barcelo, M. M. (2015) Cost effective assay choice for rare disease study designs, Orphanet journal of rare diseases 10, 10.


  31. Zhang, Z. G., Li, Y., Ng, C. T., and Song, Y. Q. (2015) Inflammation in Alzheimer's Disease and Molecular Genetics: Recent Update, Archivum immunologiae et therapiae experimentalis 63, 333-344.


  32. Ying, D., Sham, P. C., Smith, D. K., Zhang, L., Lau, Y. L., and Yang, W. (2015) HaploShare: identification of extended haplotypes shared by cases and evaluation against controls, Genome biology 16, 92.


  33. Yeung, F., Chung, P. H., Wong, K. K., and Tam, P. K. (2015) Biliary-enteric reconstruction with hepaticoduodenostomy following laparoscopic excision of choledochal cyst is associated with better postoperative outcomes: a single-centre experience, Pediatric surgery international 31, 149-153.


  34. Yeung, F., Chung, P. H., Wong, K. K., and Tam, P. K. (2015) Iatrogenic diaphragmatic hernia in paediatric patients, Pediatric surgery international 31, 589-592.


  35. Yeung, F., Chung, P. H., Tam, P. K., and Wong, K. K. (2015) Is complete resection of high-risk stage IV neuroblastoma associated with better survival?, Journal of pediatric surgery.


  36. Woo, Y. C., Cheung, B. M., Yeung, C. Y., Lee, C. H., Hui, E. Y., Fong, C. H., Tso, A. W., Tam, S., and Lam, K. S. (2015) Cardiometabolic risk profile of participants with prediabetes diagnosed by HbA1c criteria in an urban Hong Kong Chinese population over 40 years of age, Diabetic medicine : a journal of the British Diabetic Association 32, 1207-1211.


  37. Wong, L. Y., and Cheung, B. M. (2015) Modulation of cytokine responses by adrenomedullin and adrenomedullin binding protein-1 in macrophages: a novel pathway in sepsis, Hong Kong medical journal = Xianggang yi xue za zhi / Hong Kong Academy of Medicine 21 Suppl 4, 39-44.


  38. Wong, C. W., Lau, C. T., Chung, P. H., Lam, W. M., Wong, K. K., and Tam, P. K. (2015) The value of the 24-h delayed abdominal radiograph of barium enema in the diagnosis of Hirschsprung's disease, Pediatric surgery international 31, 11-15.


  39. Wong, C. W., Chung, P. H., Wong, K. K., and Tam, P. K. (2015) Pneumatosis intestinalis presenting as pneumoperitoneum in a teenage girl with pyloric stenosis, BMJ case reports 2015.


  40. Wong, C. W., Chung, P. H., Tam, P. K., and Wong, K. K. (2015) Laparoscopic versus open operation for perforated peptic ulcer in pediatric patients: A 10-year experience, Journal of pediatric surgery.


  41. Wong, C. W., Chan, I. H., Chung, P. H., Lan, L. C., Lam, W. M., Wong, K. K., and Tam, P. K. (2015) Childhood intussusception: 17-year experience at a tertiary referral centre in Hong Kong, Hong Kong medical journal = Xianggang yi xue za zhi / Hong Kong Academy of Medicine.


  42. Tu, X., Chong, W. P., Zhai, Y., Zhang, H., Zhang, F., Wang, S., Liu, W., Wei, M., Siu, N. H., Yang, H., Yang, W., Cao, W., Lau, Y. L., He, F., and Zhou, G. (2015) Functional polymorphisms of the CCL2 and MBL genes cumulatively increase susceptibility to severe acute respiratory syndrome coronavirus infection, The Journal of infection 71, 101-109.


  43. To, K. K., Lee, K. C., Wong, S. S., Lo, K. C., Lui, Y. M., Jahan, A. S., Wu, A. L., Ke, Y. H., Law, C. Y., Sze, K. H., Lau, S. K., Woo, P. C., Lam, C. W., and Yuen, K. Y. (2015) Lipid mediators of inflammation as novel plasma biomarkers to identify patients with bacteremia, The Journal of infection 70, 433-444.


  44. Tam, R. C., Lee, A. L., Yang, W., Lau, C. S., and Chan, V. S. (2015) Systemic Lupus Erythematosus Patients Exhibit Reduced Expression of CLEC16A Isoforms in Peripheral Leukocytes, International journal of molecular sciences 16, 14428-14440.


  45. Shen, J., Xiao, Z., Wu, W. K., Wang, M. H., To, K. F., Chen, Y., Yang, W., Li, M. S., Shin, V. Y., Tong, J. H., Kang, W., Zhang, L., Li, M., Wang, L., Lu, L., Chan, R. L., Wong, S. H., Yu, J., Chan, M. T., Chan, F. K., Sung, J. J., Cheng, A. S., and Cho, C. H. (2015) Epigenetic silencing of miR-490-3p reactivates the chromatin remodeler SMARCD1 to promote Helicobacter pylori-induced gastric carcinogenesis, Cancer research 75, 754-765.


  46. Shea, Y. F., Chu, L. W., Chan, A. O., Ha, J., Li, Y., and Song, Y. Q. (2015) A systematic review of familial Alzheimer's disease: Differences in presentation of clinical features among three mutated genes and potential ethnic differences, Journal of the Formosan Medical Association = Taiwan yi zhi.


  47. Plani-Lam, J. H., Chow, T. C., Siu, K. L., Chau, W. H., Ng, M. H., Bao, S., Ng, C. T., Sham, P., Shum, D. K., Ingley, E., Jin, D. Y., and Song, Y. Q. (2015) PTPN21 exerts pro-neuronal survival and neuritic elongation via ErbB4/NRG3 signaling, The international journal of biochemistry & cell biology 61, 53-62.


  48. Peng, J., Tsang, J. Y., Ho, D. H., Zhang, R., Xiao, H., Li, D., Zhu, J., Wang, F., Bian, Z., Lui, V. C., Xu, A., Tam, P. K., Lamb, J. R., Xia, H., and Chen, Y. (2015) Modulatory effects of adiponectin on the polarization of tumor-associated macrophages, International journal of cancer. Journal international du cancer 137, 848-858.


  49. Ong, K. L., Ding, J., McClelland, R. L., Cheung, B. M., Criqui, M. H., Barter, P. J., Rye, K. A., and Allison, M. A. (2015) Relationship of pericardial fat with biomarkers of inflammation and hemostasis, and cardiovascular disease: the Multi-Ethnic Study of Atherosclerosis, Atherosclerosis 239, 386-392.


  50. Ong, K. L., Ding, J., McClelland, R. L., Cheung, B. M., Criqui, M. H., Barter, P. J., Rye, K. A., and Allison, M. A. (2015) Relationship of pericardial fat with lipoprotein distribution: The Multi-Ethnic study of atherosclerosis, Atherosclerosis 241, 664-670.


  51. Marchegiani, S., Davis, T., Tessadori, F., van Haaften, G., Brancati, F., Hoischen, A., Huang, H., Valkanas, E., Pusey, B., Schanze, D., Venselaar, H., Vulto-van Silfhout, A. T., Wolfe, L. A., Tifft, C. J., Zerfas, P. M., Zambruno, G., Kariminejad, A., Sabbagh-Kermani, F., Lee, J., Tsokos, M. G., Lee, C. C., Ferraz, V., da Silva, E. M., Stevens, C. A., Roche, N., Bartsch, O., Farndon, P., Bermejo-Sanchez, E., Brooks, B. P., Maduro, V., Dallapiccola, B., Ramos, F. J., Chung, H. Y., Le Caignec, C., Martins, F., Jacyk, W. K., Mazzanti, L., Brunner, H. G., Bakkers, J., Lin, S., Malicdan, M. C., Boerkoel, C. F., Gahl, W. A., de Vries, B. B., van Haelst, M. M., Zenker, M., and Markello, T. C. (2015) Recurrent Mutations in the Basic Domain of TWIST2 Cause Ablepharon Macrostomia and Barber-Say Syndromes, American journal of human genetics 97, 99-110.


  52. Liu, J. A., Lai, F. P., Gui, H. S., Sham, M. H., Tam, P. K., Garcia-Barcelo, M. M., Hui, C. C., and Ngan, E. S. (2015) Identification of GLI Mutations in Patients With Hirschsprung Disease That Disrupt Enteric Nervous System Development in Mice, Gastroenterology.


  53. Li, Y., Kido, T., Garcia-Barcelo, M. M., Tam, P. K., Tabatabai, Z. L., and Lau, Y. F. (2015) SRY interference of normal regulation of the RET gene suggests a potential role of the Y-chromosome gene in sexual dimorphism in Hirschsprung disease, Human molecular genetics 24, 685-697.


  54. Li, T. H., Qin, Y. W., Sham, P. C., and Leung, W. K. (2015) Alterations of Human Gastric Microbiota in Patients With H. pylori Infection and Different Stages of Gastric Carcinogenesis, Gastroenterology 148, S158-S159.


  55. Li, Q., Leung, Y. O., Zhou, I., Ho, L. C., Kong, W., Basil, P., Wei, R., Lam, S., Zhang, X., Law, A. C., Chua, S. E., Sham, P. C., Wu, E. X., and McAlonan, G. M. (2015) Dietary supplementation with n-3 fatty acids from weaning limits brain biochemistry and behavioural changes elicited by prenatal exposure to maternal inflammation in the mouse model, Translational psychiatry 5, e641.


  56. Li, J., Sham, P. C., Song, Y., and Li, M. (2015) SPS: A Simulation Tool for Calculating Power of Set-Based Genetic Association Tests, Genetic epidemiology 39, 395-397.


  57. Leung, L., Wong, C. W., Chung, P. H., Wong, K. K., and Tam, P. K. (2015) Laparoscopic Nissen fundoplication for gastro-oesophageal reflux disease in infants, Pediatric surgery international 31, 83-88.


  58. Leung, L., Chung, P. H., Wong, K. K., and Tam, P. K. (2015) Management of tracheobronchial obstruction in infants using metallic stents: long-term outcome, Pediatric surgery international 31, 249-254.


  59. Lee, K. C., Tam, E. W., Lo, K. C., Tsang, A. K., Lau, C. C., To, K. K., Chan, J. F., Lam, C. W., Yuen, K. Y., Lau, S. K., and Woo, P. C. (2015) Metabolomics Analysis Reveals Specific Novel Tetrapeptide and Potential Anti-Inflammatory Metabolites in Pathogenic Aspergillus species, International journal of molecular sciences 16, 13850-13867.


  60. Lee, C. H., Woo, Y. C., Lam, J. K., Fong, C. H., Cheung, B. M., Lam, K. S., and Tan, K. C. (2015) Validation of the Pooled Cohort equations in a long-term cohort study of Hong Kong Chinese, Journal of clinical lipidology 9, 640-646 e642.


  61. Law, C. Y., Lam, C. W., Ching, C. K., Yau, K. C., Ho, T. W., Lai, C. K., and Mak, C. M. (2015) NMR-based urinalysis for beta-ketothiolase deficiency, Clinica chimica acta; international journal of clinical chemistry 438, 222-225.


  62. Lau, S. T., Hansford, L. M., Chan, W. K., Chan, G. C., Wan, T. S., Wong, K. K., Kaplan, D. R., Tam, P. K., and Ngan, E. S. (2015) Prokineticin signaling is required for the maintenance of a de novo population of c-KIT(+) cells to sustain neuroblastoma progression, Oncogene 34, 1019-1034.


  63. Lau, S. K., Sridhar, S., Ho, C. C., Chow, W. N., Lee, K. C., Lam, C. W., Yuen, K. Y., and Woo, P. C. (2015) Laboratory diagnosis of melioidosis: past, present and future, Experimental biology and medicine 240, 742-751.


  64. Lau, S. K., Lam, C. W., Curreem, S. O., Lee, K. C., Lau, C. C., Chow, W. N., Ngan, A. H., To, K. K., Chan, J. F., Hung, I. F., Yam, W. C., Yuen, K. Y., and Woo, P. C. (2015) Identification of specific metabolites in culture supernatant of Mycobacterium tuberculosis using metabolomics: exploration of potential biomarkers, Emerging microbes & infections 4, e6.


  65. Lau, S. K., Lam, C. W., Curreem, S. O., Lee, K. C., Chow, W. N., Lau, C. C., Sridhar, S., Wong, S. C., Martelli, P., Hui, S. W., Yuen, K. Y., and Woo, P. C. (2015) Metabolomic profiling of Burkholderia pseudomallei using UHPLC-ESI-Q-TOF-MS reveals specific biomarkers including 4-methyl-5-thiazoleethanol and unique thiamine degradation pathway, Cell & bioscience 5, 26.


  66. Lau, C. T., Lan, L., Wong, K., and Tam, P. K. (2015) A light bulb moment: an unusual cause of foreign body aspiration in children, BMJ case reports 2015.


  67. Lang, B. H., Yu, H. W., Lo, C. Y., Lee, K. E., Garcia-Barcelo, M. M., Woo, Y. C., Lee, P. C., Wong, K. P., Tam, P. K., and Lam, K. S. (2015) Bilateral Pheochromocytomas in MEN2A Syndrome: A Two-Institution Experience, World journal of surgery 39, 2484-2491.


  68. Lam, M. P., Cheung, B. M., and Wong, I. C. (2015) Prevalence of Potentially Inappropriate Prescribing Among Hong Kong Older Adults: A Comparison of the Beers 2003, Beers 2012, and Screening Tool of Older Person's Prescriptions and Screening Tool to Alert doctors to Right Treatment Criteria, Journal of the American Geriatrics Society 63, 1471-1472.


  69. Lam, L. C., Wong, C. S., Wang, M. J., Chan, W. C., Chen, E. Y., Ng, R. M., Hung, S. F., Cheung, E. F., Sham, P. C., Chiu, H. F., Lam, M., Chang, W. C., Lee, E. H., Chiang, T. P., Lau, J. T., van Os, J., Lewis, G., and Bebbington, P. (2015) Prevalence, psychosocial correlates and service utilization of depressive and anxiety disorders in Hong Kong: the Hong Kong Mental Morbidity Survey (HKMMS), Social psychiatry and psychiatric epidemiology 50, 1379-1388.


  70. Lam, D. C., Luo, S. Y., Deng, W., Kwan, J., Rodriguez-Canales, J., Cheung, A. L., Cheng, G. H., Lin, C. H., Wistuba, II, Sham, P. C., Wan, T. S., and Tsao, S. W. (2015) Oncogenic mutation profiling in new lung cancer and mesothelioma cell lines, OncoTargets and therapy 8, 195-209.


  71. Lam, C. W., Law, C. Y., Sze, K. H., and To, K. K. (2015) Quantitative metabolomics of urine for rapid etiological diagnosis of urinary tract infection: evaluation of a microbial-mammalian co-metabolite as a diagnostic biomarker, Clinica chimica acta; international journal of clinical chemistry 438, 24-28.


  72. Lam, C. W., Law, C. Y., Siu, W. K., Fung, C. W., Yau, M. M., Huen, K. F., Lee, H. H., and Mak, C. M. (2015) Novel POLG mutation in a patient with sensory ataxia, neuropathy, ophthalmoparesis and stroke, Clinica chimica acta; international journal of clinical chemistry 448, 211-214.


  73. Lam, C. W., Law, C. Y., Leung, K. F., Lai, C. K., Pak-lam Chen, S., Chan, B., Chan, K. Y., Yuen, Y. P., Mak, C. M., and Yan-wo Chan, A. (2015) NMR-based urinalysis for rapid diagnosis of beta-ureidopropionase deficiency in a patient with Dravet syndrome, Clinica chimica acta; international journal of clinical chemistry 440, 201-204.


  74. Kwok, H., Wu, C. W., Palser, A. L., Kellam, P., Sham, P. C., Kwong, D. L. W., and Chiang, A. K. S. (2015) Genomic Diversity of Epstein-Barr Virus Genomes Isolated from Primary Nasopharyngeal Carcinoma Biopsy Samples (vol 88, pg 10662, 2014), Journal of virology 89, 886-886.


  75. Kunutsor, S. K., Apekey, T. A., and Cheung, B. M. (2015) Gamma-glutamyltransferase and risk of hypertension: a systematic review and dose-response meta-analysis of prospective evidence, Journal of hypertension 33, 2373-2381.


  76. Huang, J. S., Lau, C. T., Wong, W. Y., Tao, Q., Wong, K. K., and Tam, P. K. (2015) Thoracoscopic repair of congenital diaphragmatic hernia: two centres' experience with 60 patients, Pediatric surgery international 31, 191-195.


  77. Ho, P. W., Pang, S. Y., Li, M., Tse, Z. H., Kung, M. H., Sham, P. C., and Ho, S. L. (2015) PMCA4 (ATP2B4) mutation in familial spastic paraplegia causes delay in intracellular calcium extrusion, Brain and behavior 5, e00321.


  78. Harris, I. S., Treloar, A. E., Inoue, S., Sasaki, M., Gorrini, C., Lee, K. C., Yung, K. Y., Brenner, D., Knobbe-Thomsen, C. B., Cox, M. A., Elia, A., Berger, T., Cescon, D. W., Adeoye, A., Brustle, A., Molyneux, S. D., Mason, J. M., Li, W. Y., Yamamoto, K., Wakeham, A., Berman, H. K., Khokha, R., Done, S. J., Kavanagh, T. J., Lam, C. W., and Mak, T. W. (2015) Glutathione and thioredoxin antioxidant pathways synergize to drive cancer initiation and progression, Cancer cell 27, 211-222.


  79. Fung, W. L., Butcher, N. J., Costain, G., Andrade, D. M., Boot, E., Chow, E. W., Chung, B., Cytrynbaum, C., Faghfoury, H., Fishman, L., Garcia-Minaur, S., George, S., Lang, A. E., Repetto, G., Shugar, A., Silversides, C., Swillen, A., van Amelsvoort, T., McDonald-McGinn, D. M., and Bassett, A. S. (2015) Practical guidelines for managing adults with 22q11.2 deletion syndrome, Genetics in medicine : official journal of the American College of Medical Genetics 17, 599-609.


  80. Chung, P. H., Wong, K. K., and Tam, P. K. (2015) Predictors for failure after Kasai operation, Journal of pediatric surgery 50, 293-296.


  81. Chung, P. H., Wong, K. K., Chan, S. C., and Tam, P. K. (2015) Liver transplant for biliary atresia is associated with a worse outcome - Myth or fact?, Journal of pediatric surgery.


  82. Cheung, C. Y. Y., Hui, E. Y. L., Kwok, K. H. M., Woo, Y. C., Lee, P. C. H., Chow, W. S., Fong, C. H. Y., Yuen, M. M. A., Wong, R. L. C., Xu, A., Wong, D. S. H., Sham, P. C., and Lam, K. S. L. (2015) Implication of genetic loci identified in genome-wide association studies of diabetic retinopathy in Chinese patients with type 2 diabetes, Diabetologia 58, S522-S522.


  83. Cheung, C. Y., Tam, S., Lam, C. W., Lie, A. K., and Kwong, Y. L. (2015) Allogeneic haematopoietic stem cell transplantation for erythropoietic protoporphyria: a cautionary note, Blood cells, molecules & diseases 54, 266-267.


  84. Cheung, B. M. (2015) Evolution of the Postgraduate Medical Journal, Postgraduate medical journal 91, 539.


  85. Cheung, A. J., and Cheung, B. M. (2015) False detection of atrial fibrillation in children by a blood pressure monitor with atrial fibrillation detection function, BMJ case reports 2015.


  86. Cheng, Z., Zhou, J., To, K. K., Chu, H., Li, C., Wang, D., Yang, D., Zheng, S., Hao, K., Bosse, Y., Obeidat, M., Brandsma, C. A., Song, Y. Q., Chen, Y., Zheng, B. J., Li, L., and Yuen, K. Y. (2015) Identification of TMPRSS2 as a Susceptibility Gene for Severe 2009 Pandemic A(H1N1) Influenza and A(H7N9) Influenza, The Journal of infectious diseases 212, 1214-1221.


  87. Cheng, W. W., Tang, C. S., Gui, H. S., So, M. T., Lui, V. C., Tam, P. K., and Garcia-Barcelo, M. M. (2015) Depletion of the IKBKAP ortholog in zebrafish leads to hirschsprung disease-like phenotype, World journal of gastroenterology : WJG 21, 2040-2046.


  88. Chen, Y., Zhou, J., Cheng, Z., Yang, S., Chu, H., Fan, Y., Li, C., Wong, B. H., Zheng, S., Zhu, Y., Yu, F., Wang, Y., Liu, X., Gao, H., Yu, L., Tang, L., Cui, D., Hao, K., Bosse, Y., Obeidat, M., Brandsma, C. A., Song, Y. Q., To, K. K., Sham, P. C., Yuen, K. Y., and Li, L. (2015) Functional variants regulating LGALS1 (Galectin 1) expression affect human susceptibility to influenza A(H7N9), Scientific reports 5, 8517.


  89. Chaudhry, A., Noor, A., Degagne, B., Baker, K., Bok, L. A., Brady, A. F., Chitayat, D., Chung, B. H., Cytrynbaum, C., Dyment, D., Filges, I., Helm, B., Hutchison, H. T., Jeng, L. J., Laumonnier, F., Marshall, C. R., Menzel, M., Parkash, S., Parker, M. J., Study, D. D. D., Raymond, L. F., Rideout, A. L., Roberts, W., Rupps, R., Schanze, I., Schrander-Stumpel, C. T., Speevak, M. D., Stavropoulos, D. J., Stevens, S. J., Thomas, E. R., Toutain, A., Vergano, S., Weksberg, R., Scherer, S. W., Vincent, J. B., and Carter, M. T. (2015) Phenotypic spectrum associated with PTCHD1 deletions and truncating mutations includes intellectual disability and autism spectrum disorder, Clinical genetics 88, 224-233.


  90. Chang, W. C., Wong, C. S. M., Lam, L. C. W., Lee, E. H. M., Chen, E. Y. H., Chan, W. C., Ng, R. R. M., Hung, S. F., Cheung, E. F. C., Sham, P. C., Chiu, H. F. K., Lam, M., Chiang, T. P., Lau, J. T. F., van Os, J., Lewis, G., and Bebbington, P. (2015) Prevalence, Psychosocial and Physical Health Correlates of Psychotic Disorders in Hong Kong: The Hong Kong Mental Health Morbidity Survey, Schizophrenia bulletin 41, S135-S135.




  91. Chan, Y. H., Lau, K. K., Yiu, K. H., Li, S. W., Tam, S., Lam, T. H., Lau, C. P., Siu, C. W., Cheung, B. M., and Tse, H. F. (2015) Vascular protective effects of statin-related increase in serum 25-hydroxyvitamin D among high-risk cardiac patients, Journal of cardiovascular medicine 16, 51-58.