2013 Research Publications

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  1. Bao, S., Zhou, X., Zhang, L., Zhou, J., To, K. K., Wang, B., Wang, L., Zhang, X., and Song, Y. Q. (2013) Prioritizing genes responsible for host resistance to influenza using network approaches, BMC genomics 14, 816.

     
  2. Chan, I. H., Lau, C. T., Chung, P. H., Chan, K. L., Lan, L. C., Wong, K. K., and Tam, P. K. (2013) Laparoscopic inguinal hernia repair in premature neonates: is it safe?, Pediatric surgery international 29, 327-330.

     
  3. Chan, L. S., Lo, J. L., Kumana, C. R., and Cheung, B. M. (2013) Utility of infrared thermography for screening febrile subjects, Hong Kong medical journal = Xianggang yi xue za zhi / Hong Kong Academy of Medicine 19, 109-115.

     
  4. Cheng, G., Tang, C. S., Wong, E. H., Cheng, W. W., So, M. T., Miao, X., Zhang, R., Cui, L., Liu, X., Ngan, E. S., Lui, V. C., Chung, P. H., Chan, I. H., Liu, J., Zhong, W., Xia, H., Yu, J., Qiu, X., Wu, X. Z., Wang, B., Dong, X., Tou, J., Huang, L., Yi, B., Ren, H., Chan, E. K., Ye, K., O'Reilly, P. F., Wong, K. K., Sham, P. C., Cherny, S. S., Tam, P. K., and Garcia-Barcelo, M. M. (2013) Common genetic variants regulating ADD3 gene expression alter biliary atresia risk, Journal of hepatology 59, 1285-1291.

     
  5. Cheng, G. L., Zeng, H., Leung, M. K., Zhang, H. J., Lau, B. W., Liu, Y. P., Liu, G. X., Sham, P. C., Chan, C. C., So, K. F., and Lee, T. M. (2013) Heroin abuse accelerates biological aging: a novel insight from telomerase and brain imaging interaction, Translational psychiatry 3, e260.

     
  6. Cheng, T., Xia, W., Wang, P., Huang, F., Wang, J., and Sun, H. (2013) Histidine-rich proteins in prokaryotes: metal homeostasis and environmental habitat-related occurrence, Metallomics : integrated biometal science.

     
  7. Cheung, B. M., Cheung, T. T., and Samaranayake, N. R. (2013) Safety of antiobesity drugs, Therapeutic advances in drug safety 4, 171-181.

     
  8. Cheung, C. L., Cheung, T. T., Lam, K. S., and Cheung, B. M. (2013) Reduced serum beta-trace protein is associated with metabolic syndrome, Atherosclerosis 227, 404-407.

     
  9. Cheung, C. L., Lam, K. S., and Cheung, B. M. (2013) Serum beta-2 microglobulin concentration predicts cardiovascular and all-cause mortality, International journal of cardiology 168, 4811-4813.

     
  10. Cheung, C. L., Lau, K. S., Sham, P. C., Tan, K. C., and Kung, A. W. (2013) Genetic variant in vitamin D binding protein is associated with serum 25-hydroxyvitamin D and vitamin D insufficiency in southern Chinese, Journal of human genetics 58, 749-751.

     
  11. Cheung, C. L., Cheung, T. T., Lam, K. S., and Cheung, B. M. (2013) High ferritin and low transferrin saturation are associated with pre-diabetes among a national representative sample of U.S. adults, Clinical nutrition 32, 1055-1060.

     
  12. Cheung, C. L., Tan, K. C., Lam, K. S., and Cheung, B. M. (2013) The relationship between glucose metabolism, metabolic syndrome, and bone-specific alkaline phosphatase: a structural equation modeling approach, The Journal of clinical endocrinology and metabolism 98, 3856-3863.

     
  13. Cheung, C. L., Lau, K. S., Sham, P. C., Tan, K. C., and Kung, A. W. (2013) Genetic variants in GREM2 are associated with bone mineral density in a southern Chinese population, The Journal of clinical endocrinology and metabolism 98, E1557-1561.

     
  14. Cheung, C. L., Lam, K. S., and Cheung, B. M. (2013) Serum beta-2 microglobulin predicts mortality in people with diabetes, European journal of endocrinology / European Federation of Endocrine Societies 169, 1-7.

     
  15. Cho, S. Y., Goh, D. L., Lau, K. C., Ong, H. T., and Lam, C. W. (2013) Microarray analysis unmasked paternal uniparental disomy of chromosome 12 in a patient with isolated sulfite oxidase deficiency, Clinica chimica acta; international journal of clinical chemistry 426, 13-17.

     
  16. Cho, S. Y., Siu, T. S., Ma, O., Tam, S., and Lam, C. W. (2013) Novel mutations in myopathic form of carnitine palmitoyltransferase II deficiency in a Chinese patient, Clinica chimica acta; international journal of clinical chemistry 425, 125-127.

     
  17. Cho, S. Y., Lam, C. W., Tong, S. F., and Siu, W. K. (2013) X-linked glycogen storage disease IXa manifested in a female carrier due to skewed X chromosome inactivation, Clinica chimica acta; international journal of clinical chemistry 426, 75-78.

     
  18. Chow, W. S., Tso, A. W., Xu, A., Yuen, M. M., Fong, C. H., Lam, T. H., Lo, S. V., Tse, H. F., Woo, Y. C., Yeung, C. Y., Cheung, B. M., and Lam, K. S. (2013) Elevated circulating adipocyte-fatty acid binding protein levels predict incident cardiovascular events in a community-based cohort: a 12-year prospective study, Journal of the American Heart Association 2, e004176.

     
  19. Chow, W. S., Xu, A., Woo, Y. C., Tso, A. W., Cheung, S. C., Fong, C. H., Tse, H. F., Chau, M. T., Cheung, B. M., and Lam, K. S. (2013) Serum fibroblast growth factor-21 levels are associated with carotid atherosclerosis independent of established cardiovascular risk factors, Arteriosclerosis, thrombosis, and vascular biology 33, 2454-2459.

     
  20. Cui, L., Wong, E. H., Cheng, G., Firmato de Almeida, M., So, M. T., Sham, P. C., Cherny, S. S., Tam, P. K., and Garcia-Barcelo, M. M. (2013) Genetic Analyses of a Three Generation Family Segregating Hirschsprung Disease and Iris Heterochromia, PloS one 8, e66631.

     
  21. El-Nezami, H., Tam, P. K., Chan, Y., Lau, A. S., Leung, F. C., Chen, S. F., Lan, L. C., and Wang, M. F. (2013) Impact of melamine-tainted milk on foetal kidneys and disease development later in life, Hong Kong medical journal = Xianggang yi xue za zhi / Hong Kong Academy of Medicine 19 Suppl 8, 34-38.

     
  22. Gui, H., Tang, W. K., So, M. T., Proitsi, P., Sham, P. C., Tam, P. K., Sau-Wai Ngan, E., Cherny, S. S., and Garcia-Barcelo, M. M. (2013) RET and NRG1 interplay in Hirschsprung disease, Human genetics 132, 591-600.

     
  23. Hui, C. L., Chang, W. C., Chan, S. K., Lee, E. H., Tam, W. W., Lai, D. C., Wong, G. H., Tang, J. Y., Li, F. W., Leung, K. F., McGhee, S. M., Sham, P. C., and Chen, E. Y. (2013) Early intervention and evaluation for adult-onset psychosis: the JCEP study rationale and design, Early intervention in psychiatry.

     
  24. Kwok, C. K., Tam, P. K., and Ngan, E. S. (2013) Potential use of skin-derived precursors (SKPs) in establishing a cell-based treatment model for Hirschsprung's disease, Journal of pediatric surgery 48, 619-628.

     
  25. Lam, C. W., and Mak, C. M. (2013) Allele dropout caused by a non-primer-site SNV affecting PCR amplification--a call for next-generation primer design algorithm, Clinica chimica acta; international journal of clinical chemistry 421, 208-212.

     
  26. Lam, M. P., Yeung, C. K., and Cheung, B. M. (2013) Pharmacogenetics of allopurinol--making an old drug safer, Journal of clinical pharmacology 53, 675-679.

     
  27. Lau, C. T., Leung, L., Chan, I. H., Chung, P. H., Lan, L. C., Chan, K. L., Wong, K. K., and Tam, P. K. (2013) Thoracoscopic resection of congenital cystic lung lesions is associated with better post-operative outcomes, Pediatric surgery international 29, 341-345.

     
  28. Lei, S., Li, H., Xu, J., Liu, Y., Gao, X., Wang, J., Ng, K. F., Lau, W. B., Ma, X. L., Rodrigues, B., Irwin, M. G., and Xia, Z. (2013) Hyperglycemia-induced protein kinase C beta2 activation induces diastolic cardiac dysfunction in diabetic rats by impairing caveolin-3 expression and Akt/eNOS signaling, Diabetes 62, 2318-2328.

     
  29. Li, C., Cheung, C. L., Cheung, T. T., Samaranayake, N. R., and Cheung, B. M. (2013) Hay fever and hypertension in the US adult population, Clinical and experimental hypertension.

     
  30. Li, H., Liu, Z., Wang, J., Wong, G. T., Cheung, C. W., Zhang, L., Chen, C., Xia, Z., and Irwin, M. G. (2013) Susceptibility to myocardial ischemia reperfusion injury at early stage of type 1 diabetes in rats, Cardiovascular diabetology 12, 133.

     
  31. Li, M., Pang, S. Y., Song, Y., Kung, M. H., Ho, S. L., and Sham, P. C. (2013) Whole exome sequencing identifies a novel mutation in the transglutaminase 6 gene for spinocerebellar ataxia in a Chinese family, Clinical genetics 83, 269-273.

     
  32. Li, M. J., Wang, L. Y., Xia, Z., Sham, P. C., and Wang, J. (2013) GWAS3D: Detecting human regulatory variants by integrative analysis of genome-wide associations, chromosome interactions and histone modifications, Nucleic acids research 41, W150-158.

     
  33. Li, M. X., Kwan, J. S., Bao, S. Y., Yang, W., Ho, S. L., Song, Y. Q., and Sham, P. C. (2013) Predicting mendelian disease-causing non-synonymous single nucleotide variants in exome sequencing studies, PLoS genetics 9, e1003143.

     
  34. Li, P. H., Wong, W. H., Lee, T. L., Lau, C. S., Chan, T. M., Leung, A. M., Tong, K. L., Tse, N. K., Mok, C. C., Wong, S. N., Lee, K. W., Ho, M. H., Lee, P. P., Chong, C. Y., Wong, R. W., Mok, M. Y., Ying, S. K., Fung, S. K., Lai, W. M., Yang, W., and Lau, Y. L. (2013) Relationship between autoantibody clustering and clinical subsets in SLE: cluster and association analyses in Hong Kong Chinese, Rheumatology 52, 337-345.

     
  35. Liao, S. B., Wong, P. F., Wso, Cheung, B. M., and Tang, F. (2013) Effects of adrenomedullin on tumour necrosis factor alpha, interleukins, endothelin-1, leptin, and adiponectin in the epididymal fat and soleus muscle of the rat, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 45, 31-37.

     
  36. Liu, A. P., Tang, W. F., Lau, E. T., Chan, K. Y., Kan, A. S., Wong, K. Y., Tso, W. W., Jalal, K., Lee, S. L., Chau, C. S., and Chung, B. H. (2013) Expanded Prader-Willi syndrome due to chromosome 15q11.2-14 deletion: report and a review of literature, American journal of medical genetics. Part A 161A, 1309-1318.

     
  37. Liu, J., Xiao, Z., Wong, S. K., Tin, V. P., Ho, K. Y., Wang, J., Sham, M. H., and Wong, M. P. (2013) Lung cancer tumorigenicity and drug resistance are maintained through ALDH(hi)CD44(hi) tumor initiating cells, Oncotarget 4, 1698-1711.

     
  38. Man, E., Lafferty, K. A., Funke, B. H., Lun, K. S., Chan, S. Y., Chau, A. K., and Chung, B. H. (2013) NGS identifies TAZ mutation in a family with X-linked dilated cardiomyopathy, BMJ case reports 2013.

     
  39. Qin, J., Li, M. J., Wang, P., Wong, N. S., Wong, M. P., Xia, Z., Tsao, G. S., Zhang, M. Q., and Wang, J. (2013) ProteoMirExpress: inferring microRNA-centered regulatory networks from high throughput proteomic and mRNA expression data, Molecular & cellular proteomics : MCP.

     
  40. Samaranayake, N. R., Cheung, S. T., Chui, W. C., and Cheung, B. M. (2013) The pattern of the discovery of medication errors in a tertiary hospital in Hong Kong, International journal of clinical pharmacy 35, 432-438.

     
  41. Seto, W. K., Wong, D. K., Kopaniszen, M., Proitsi, P., Sham, P. C., Hung, I. F., Fung, J., Lai, C. L., and Yuen, M. F. (2013) HLA-DP and IL28B polymorphisms: influence of host genome on hepatitis B surface antigen seroclearance in chronic hepatitis B, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 56, 1695-1703.

     
  42. Shea, Y. F., Chu, L. W., Zhou, L., Li, W. M., Lin, O. Y., Chan, M. N., Xu, A., Wong, R., Ho, T. Y., Liu, K. W., Ha, J., Daniel, T. W., Song, Y. Q., and Lam, K. S. (2013) Cerebrospinal fluid biomarkers of Alzheimer's disease in Chinese patients: a pilot study, American journal of Alzheimer's disease and other dementias 28, 769-775.

     
  43. Shum, C. K., Lau, S. T., Tsoi, L. L., Chan, L. K., Yam, J. W., Ohira, M., Nakagawara, A., Tam, P. K., and Ngan, E. S. (2013) Kruppel-like factor 4 (KLF4) suppresses neuroblastoma cell growth and determines non-tumorigenic lineage differentiation, Oncogene 32, 4086-4099.

     
  44. Tam, P. K., Wong, K. K., Li, L., and Zhang, J. Z. (2013) Internationalization: the Hong Kong-China experience as a model for collaborative education in Asia, Pediatric surgery international 29, 1053-1059.

     
  45. To, K. K., Fung, A. M., Teng, J. L., Curreem, S. O., Lee, K. C., Yuen, K. Y., Lam, C. W., Lau, S. K., and Woo, P. C. (2013) Characterization of a Tsukamurella pseudo-outbreak by phenotypic tests, 16S rRNA sequencing, pulsed-field gel electrophoresis, and metabolic footprinting, Journal of clinical microbiology 51, 334-338.

     
  46. Tse, H. F., Ho, J. C., Choi, S. W., Lee, Y. K., Butler, A. W., Ng, K. M., Siu, C. W., Simpson, M. A., Lai, W. H., Chan, Y. C., Au, K. W., Zhang, J., Lay, K. W., Esteban, M. A., Nicholls, J. M., Colman, A., and Sham, P. C. (2013) Patient-specific induced-pluripotent stem cells-derived cardiomyocytes recapitulate the pathogenic phenotypes of dilated cardiomyopathy due to a novel DES mutation identified by whole exome sequencing, Human molecular genetics 22, 1395-1403.

     
  47. Wang, P., Lai, W. F., Li, M. J., Xu, F., Yalamanchili, H. K., Lovell-Badge, R., and Wang, J. (2013) Inference of gene-phenotype associations via protein-protein interaction and orthology, PloS one 8, e77478.

     
  48. Wang, T., Mao, X., Li, H., Qiao, S., Xu, A., Wang, J., Lei, S., Liu, Z., Ng, K. F., Wong, G. T., Vanhoutte, P. M., Irwin, M. G., and Xia, Z. (2013) N-Acetylcysteine and allopurinol up-regulated the Jak/STAT3 and PI3K/Akt pathways via adiponectin and attenuated myocardial postischemic injury in diabetes, Free radical biology & medicine 63, 291-303.

     
  49. Wang Z, Cui J, Wong WM, Li X, Xue W, Lin R, Wang J, Wang P, Tanner JA, Cheah KS et al.  2013.  Kif5b controls the localization of myofibril components for their assembly and linkage to the myotendinous junctions.  Development 140(3): 617-626.

     
  50. Wong, E. H., Cui, L., Ng, C. L., Tang, C. S., Liu, X. L., So, M. T., Yip, B. H., Cheng, G., Zhang, R., Tang, W. K., Yang, W., Lau, Y. L., Baum, L., Kwan, P., Sun, L. D., Zuo, X. B., Ren, Y. Q., Yin, X. Y., Miao, X. P., Liu, J., Lui, V. C., Ngan, E. S., Yuan, Z. W., Zhang, S. W., Xia, J., Wang, H., Sun, X. B., Wang, R., Chang, T., Chan, I. H., Chung, P. H., Zhang, X. J., Wong, K. K., Cherny, S. S., Sham, P. C., Tam, P. K., and Garcia-Barcelo, M. M. (2013) Genome-wide copy number variation study in anorectal malformations, Human molecular genetics 22, 621-631.

     
  51. Wong, E. H., Ng, C. L., Lui, V. C., So, M. T., Cherny, S. S., Sham, P. C., Tam, P. K., and Garcia-Barcelo, M. M. (2013) Gene network analysis of candidate loci for human anorectal malformations, PloS one 8, e69142.

     
  52. Wong, H. K., Ong, K. L., Leung, R. Y., Cheung, T. T., Xu, A., Lam, T. H., Lam, K. S., and Cheung, B. M. (2013) Plasma level of adrenomedullin is influenced by a single nucleotide polymorphism in the adiponectin gene, PloS one 8, e70335.

     
  53. Wong, H. K., Ong, K. L., Leung, R. Y., Lam, T. H., Thomas, G. N., Lam, K. S., and Cheung, B. M. (2013) A single nucleotide polymorphism of interleukin-6 gene is related to plasma adrenomedullin levels, Clinical endocrinology 79, 504-509.

     
  54. Wong, M. Y., Tang, H. W., Man, S. H., Lam, C. W., Che, C. M., and Ng, K. M. (2013) Electrospray ionization on porous spraying tips for direct sample analysis by mass spectrometry: enhanced detection sensitivity and selectivity using hydrophobic/hydrophilic materials as spraying tips, Rapid communications in mass spectrometry : RCM 27, 713-721.

     
  55. Xiao, S. M., Kung, A. W., Sham, P. C., and Tan, K. C. (2013) Genetic analysis of recently identified osteoporosis susceptibility genes in southern Chinese, The Journal of clinical endocrinology and metabolism 98, E1827-1834.

     
  56. Yang, W., Tang, H., Zhang, Y., Tang, X., Zhang, J., Sun, L., Yang, J., Cui, Y., Zhang, L., Hirankarn, N., Cheng, H., Pan, H. F., Gao, J., Lee, T. L., Sheng, Y., Lau, C. S., Li, Y., Chan, T. M., Yin, X., Ying, D., Lu, Q., Leung, A. M., Zuo, X., Chen, X., Tong, K. L., Zhou, F., Diao, Q., Tse, N. K., Xie, H., Mok, C. C., Hao, F., Wong, S. N., Shi, B., Lee, K. W., Hui, Y., Ho, M. H., Liang, B., Lee, P. P., Cui, H., Guo, Q., Chung, B. H., Pu, X., Liu, Q., Zhang, X., Zhang, C., Chong, C. Y., Fang, H., Wong, R. W., Sun, Y., Mok, M. Y., Li, X. P., Avihingsanon, Y., Zhai, Z., Rianthavorn, P., Deekajorndej, T., Suphapeetiporn, K., Gao, F., Shotelersuk, V., Kang, X., Ying, S. K., Zhang, L., Wong, W. H., Zhu, D., Fung, S. K., Zeng, F., Lai, W. M., Wong, C. M., Ng, I. O., Garcia-Barcelo, M. M., Cherny, S. S., Shen, N., Tam, P. K., Sham, P. C., Ye, D. Q., Yang, S., Zhang, X., and Lau, Y. L. (2013) Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lupus erythematosus in Asians, American journal of human genetics 92, 41-51.

     
  57. Yeung, C. Y., Tso, A. W., Xu, A., Wang, Y., Woo, Y. C., Lam, T. H., Lo, S. V., Fong, C. H., Wat, N. M., Woo, J., Cheung, B. M., and Lam, K. S. (2013) Pro-inflammatory adipokines as predictors of incident cancers in a Chinese cohort of low obesity prevalence in Hong Kong, PloS one 8, e78594.

     
  58. Yiu, Y. F., Yiu, K. H., Siu, C. W., Chan, Y. H., Li, S. W., Wong, L. Y., Lee, S. W., Tam, S., Wong, E. W., Lau, C. P., Cheung, B. M., and Tse, H. F. (2013) Randomized controlled trial of vitamin D supplement on endothelial function in patients with type 2 diabetes, Atherosclerosis 227, 140-146.

     
  59. Yung, J. S., Tam, P. K., and Ngan, E. S. (2013) Pluripotent stem cell for modeling neurological diseases, Experimental cell research 319, 177-184.

     
  60. Zayts, O., Sarangi, S., Thong, M. K., Chung, B. H., Lo, I. F., Kan, A. S., Lee, J. M., Padilla, C. D., Cutiongco-de la Paz, E. M., Faradz, S. M., and Wasant, P. (2013) Genetic counseling/consultation in South-East Asia: a report from the workshop at the 10th Asia pacific conference on human genetics, Journal of genetic counseling 22, 917-924.

     
  61. Zhang, J., Zhang, Y., Yang, J., Zhang, L., Sun, L., Pan, H. F., Hirankarn, N., Ying, D., Zeng, S., Lee, T. L., Lau, C. S., Chan, T. M., Leung, A. M., Mok, C. C., Wong, S. N., Lee, K. W., Ho, M. H., Lee, P. P., Chung, B. H., Chong, C. Y., Wong, R. W., Mok, M. Y., Wong, W. H., Tong, K. L., Tse, N. K., Li, X. P., Avihingsanon, Y., Rianthavorn, P., Deekajorndej, T., Suphapeetiporn, K., Shotelersuk, V., Ying, S. K., Fung, S. K., Lai, W. M., Garcia-Barcelo, M. M., Cherny, S. S., Tam, P. K., Sham, P. C., Yang, S., Ye, D. Q., Zhang, X. J., Lau, Y. L., and Yang, W. (2013) Three SNPs in chromosome 11q23.3 are Independently Associated with Systemic Lupus Erythematosus in Asians, Human molecular genetics.

     
  62. Zhang, J., Zhang, Y., Zhang, L., Yang, J., Ying, D., Zeng, S., Lee, T. L., Lau, C. S., Chan, T. M., Leung, A. M., Mok, C. C., Wong, S. N., Lee, K. W., Ho, M. H., Lee, P. P., Chung, B. H., Chong, C. Y., Wong, R. W., Mok, M. Y., Wong, W. H., Lau, Y. L., and Yang, W. (2013) Epistatic interaction between genetic variants in susceptibility gene ETS1 correlates with IL-17 levels in SLE patients, Annals of human genetics 77, 344-350.

     
  63. Zhang, L., Zhang, J., Yang, J., Ying, D., Lau, Y. L., and Yang, W. (2013) PriVar: a toolkit for prioritizing SNVs and indels from next-generation sequencing data, Bioinformatics 29, 124-125.