Home Technology Seminars

Technology Seminar (16 June 2011)



Technology Seminar

Tumor Microenvironment:
Role in Tumor Growth & Metastasis and
Investigative Tools


Dr. George McBride

Field Applications Manager - Asia

16 June 2011 (Thu)

3:00 – 4:30pm

Room L6-32, 6/F, Laboratory Block

Li Ka Shing Faculty of Medicine Building

21 Sassoon Road, Pokfulam, Hong Kong



Transformation of normal cell into neoplastic and metastatic phenotype is aided by several surrounding components that are collectively known as the tumor microenvironment. The composition of this microenvironment is highly variable and is frequently altered during tumor progression. Tumor cells often face conditions, such as hypoxia, low pH, and low glucose levels, which result in mutation to survive under harsh conditions and acquire drug resistance.

To overcome hypoxic conditions, tumor cells secrete VEGF and other angiogenic growth factors that enhance neovascularization. This obligatory neovascularization makes angiogenesis and microenvironment prominent targets for therapeutic intervention.

This presentation will highlight roles of microenvironmental factors in tumor growth & metastasis and introduce various investigative tools to study angiogenesis and tumor microenvironment.



Kind Reminder: Please take off your lab coat before coming to the seminar.

Co-organized with Merck Millipore
Refreshment to be served

For enquiries, please call 2819-9848 or write to This e-mail address is being protected from spambots. You need JavaScript enabled to view it