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Technology Seminar (13 May 2016)



Technology Seminar

Direct, Multiplexed, Digital Detection of Biomarkers (DNA, RNA, and Protein) Using Molecular Barcodes on the NanoString nCounter System


Mr Paul Rasmussen
Director of Asia Pacific Operations

13 May 2016 (Fri)
3:30 – 4:30 pm

Seminar Room 1A, G/F
The Hong Kong Jockey Club Building for Interdisciplinary Research
5 Sassoon Road, Pokfulam, Hong Kong


The NanoString nCounter platform enables profiling of up to 800 analytes from a single sample, facilitating high resolution examination of pathways, as well as prognostic signatures. Though the technology was originally designed for gene expression profiling, it has since been adapted to enable quantitation of miRNAs, CNVs, SNVs, and proteins. Most recently, the technology has been enhanced to support 3D Biology, in which combinations and permutations of these analyses can be combined from single samples. This can be done from clinically critical but challenging samples, including from Formalin Fixed Paraffin Embedded tissue. This presentation will provide an overview of 1) the core molecular barcoding technology, 2) examples of how it can be adapted to various analytes and 3) examples of relevant research enabled by the technology.


Paul Rasmussen has overseen the Asia Pacific Market for NanoString since it’s first expansion into the region 5 years ago, including serving as the Director of Asia Pacific Operations, based in Singapore, for the last 3 years. Prior to that, Paul held various sales, technical, and market development roles based in the USA with NanoString dating back the original formation of it’s commercial operations in 2008. Before joining NanoString, Paul spent 9 years in various training, applications, and commercial roles at Applied Biosystems involved in developing their qPCR, microarray, and sequencing businesses. Before moving to industry, Paul worked in the field of DNA forensics, helping to develop the first major mitochondrial forensics reference database with the US FBI, and also conducted several linkage mapping studies which lead to the discovery of trinucleotide repeat disorder related genes responsible for certain types of Myotonic Dystrophy and Spinocerebellar Ataxia.



Co-organized with Cold Spring Biotech Corp.

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