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Joint Research Seminar (28 Jan 2016)

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Joint Research Seminar

Genomics Strategic Research Theme
Centre for Genomic Sciences

Single Cell Sequencing from Technology
to Biology and Medicine

Dr Xinghua PAN

Research Scientist
Department of Genetics
Yale University School of Medicine


28 January 2016 (Thu)
10:30 – 11:30 am


Seminar Room 1A, G/F
The Hong Kong Jockey Club Building for Interdisciplinary Research

5 Sassoon Road, Pokfulam, Hong Kong

 
Abstract:

Single cell sequencing mainly refers to sequencing the whole or the exome of a genome, a transcriptome, an epigenome, or a panel of target genes/elements of these parameters, from single cells. It provides unique power for analysis of biologically heterogeneous system, addressing its complicated functional subpopulations and uncovering its new functions. Recently, a series of technology breakthroughs were obtained, and the single cell sequencing-based studies particularly on cancer, development, neuron, and immune cells also led a wave of significant findings that are otherwise impossible. In clinical practice, it particularly accelerates development of non-invasive and ultra-sensitive methods for in vitro gene diagnosis and genomic screening of prenatal and preimplantation embryos, and for dynamic monitoring of cancer progress for personalized and precise medicine. We have developed a series of omics technologies on single cell sequencing for these applications.


About the Speaker:

Dr Xinghua Pan is a research faculty member at Department of Genetics, Yale School of Medicine. He obtained PhD from Fudan University in Shanghai, MD from Southern Medical University in Guangzhou. Since 2004, as a Research Scientist, he leads a team focusing on development of novel approaches for single cell omics analysis, and combination with NGS in translational medicine. He once worked as a leader at Molecular Staging Inc. for developing whole genome amplification technology, REPLIg.

 

ALL ARE WELCOME


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